𝔖 Bobbio Scriptorium
✦   LIBER   ✦

MR elastography of the lung with hyperpolarized 3He

✍ Scribed by Kiaran P. McGee; Rolf D. Hubmayr; R.L. Ehman

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
279 KB
Volume
59
Category
Article
ISSN
0740-3194

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

MR elastography (MRE) is a phase contrast–based technique for spatially mapping the mechanical properties of tissue‐like materials. While hyperpolarized noble gases such as helium‐3 (^3^He) have proven to be an ideal contrast mechanism for imaging of the lung using conventional MR techniques, their applicability for lung MRE is unknown, due to the fact that gases do not support shear. In this study, we report on the application of MRE to an ex vivo porcine lung specimen inflated with a hyperpolarized noble gas. Unlike proton MRE, shear wave propagation is encoded into the gas entrapped within the alveolar spaces rather than the parenchyma itself. These data provide first evidence of the technical feasibility of MRE of the lung using hyperpolarized noble gases. Magn Reson Med, 2007. Β© 2007 Wiley‐Liss, Inc.

πŸ“œ SIMILAR VOLUMES

Hyperpolarized 3He MRI of mouse lung
Hyperpolarized 3He MRI of mouse lung
✍ Joseph P. Dugas; Joel R. Garbow; Dale K. Kobayashi; Mark S. Conradi πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 480 KB

## Abstract Hyperpolarized ^3^He images of mouse lung are presented. Ventilation images and measurements of ^3^He apparent diffusion coefficient (ADC) are reported in healthy mice, and preliminary studies of emphysema and lung cancer in mice are described using these techniques. The design and oper

Hyperpolarized 3He MR lung ventilation i
Hyperpolarized 3He MR lung ventilation imaging in asthmatics: Preliminary findings
✍ Talissa A. Altes; Patrick L. Powers; Jack Knight-Scott; Gary Rakes; Thomas A.E. πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 178 KB

## Abstract Asthma is a disease characterized by chronic inflammation and reversible obstruction of the small airways resulting in impaired pulmonary ventilation. Hyperpolarized ^3^He magnetic resonance (MR) lung imaging is a new technology that provides a detailed image of lung ventilation. Hyperp

Diffusional kurtosis imaging in the lung
Diffusional kurtosis imaging in the lung using hyperpolarized 3He
✍ Robert Trampel; Jens H. Jensen; Ray F. Lee; Igor Kamenetskiy; Georgeann McGuinne πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 270 KB

## Abstract Diseases of the small airspaces represent an increasingly important health problem. Asthma is primarily a disease of airway dysfunction, while chronic obstructive pulmonary disease (COPD) is associated with abnormalities in both the small airways and the alveoli. Conventional diffusion