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Assembly of Alzheimer-like, insoluble filaments from brain cerebrosides

โœ Scribed by Warren J. Goux; Houston Smith; Dennis R. Sparkman

Book ID
116124730
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
757 KB
Volume
192
Category
Article
ISSN
0304-3940

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Alzheimer's disease is characterized by the progressive deposition of two types of fibers in the affected brains, the amyloid fibers (consisting of the Abeta peptide, generating the amyloid plaques) and paired helical filaments (PHFs, made up of tau protein, forming the neurofibrillary tangles). Whi