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Assembly and dynamics of the actin filament system in nonmuscle cells

โœ Scribed by Thomas D. Pollard

Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
549 KB
Volume
31
Category
Article
ISSN
0730-2312

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โœฆ Synopsis

Kinetic analysis has provided a detailed quantitative description of the mechanism of actin polymerization as well as the methods to analyze the mechanisms of action of actin-binding proteins. In Acanthamoeba, five different proteins regulate the pool of monomers available for polymerization, cap the end of filaments, sever filaments, and cross-link filaments. Remarkably, many of these interactions involve very-low-affinity bonds between the protein molecules.

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