We have previously reported that a physiological range of shear stress induces neutrophil homotypic aggregation mediated by lymphocyte function-associated antigen-I (LFA-1) and intercellular adhesion rnolecule-3 (ICAM-3) interactions. To further characterize the homotypic aggregation, actin polymeri
Assembly dynamics of actin in adherent human neutrophils
β Scribed by Wang, Jia-Sheng ;Pavlotsky, Nelli ;Tauber, Alfred I. ;Zaner, Ken S.
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 873 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0886-1544
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A mathematical model is proposed for describing the dynamics of the chemotactic peptide-stimulated actin polymerization response in human neutrophils. The response pathway utilizes the guanine nucleotide binding protein (G-protein) signal transduction cascade common to many receptor systems and allo
Kinetic analysis has provided a detailed quantitative description of the mechanism of actin polymerization as well as the methods to analyze the mechanisms of action of actin-binding proteins. In Acanthamoeba, five different proteins regulate the pool of monomers available for polymerization, cap th
Eosinophils represent major effector cells in the allergic inflammation. In contrast to neutrophils, the mechanism of eosinophil activation during the inflammatory response is poorly understood. In this study, the relation between calcium fluxes, chemotaxis, and actin polymerization in eosinophils f
Pentoxifylline is used clinically for the treatment of intermittent claudication. It is believed to exert its effect by altering the rheologic properties of blood. The cytoskeleton plays an important role in the maintenance of cell structure and function. In particular, alterations in the state of a