Aspirin Use, Tumor PIK3CA Mutation, and Colorectal-Cancer Survival
β Scribed by Liao, Xiaoyun; Lochhead, Paul; Nishihara, Reiko; Morikawa, Teppei; Kuchiba, Aya; Yamauchi, Mai; Imamura, Yu; Qian, Zhi Rong; Baba, Yoshifumi; Shima, Kaori; Sun, Ruifang; Nosho, Katsuhiko; Meyerhardt, Jeffrey A.; Giovannucci, Edward; Fuchs, Charles S.; Chan, Andrew T.; Ogino, Shuji
- Book ID
- 115543759
- Publisher
- Massachusetts Medical Society
- Year
- 2012
- Tongue
- English
- Weight
- 606 KB
- Volume
- 367
- Category
- Article
- ISSN
- 0096-6762
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The PI3KβAKT pathway is activated in a variety of human cancers, resulting in disturbance of cell growth, proliferation and survival. Among the factors affecting the pathway, the __KβRas__ mutation and __PIK3CA__ mutation are the most common oncogenic alterations in colorectal cancer. W
## Abstract Somatic mutations of the __PIK3CA__ gene have recently been detected in various human cancers, including sporadic colorectal cancer. However, mutations of the __PIK3CA__ gene in hereditary colorectal cancers have not been clarified. To elucidate the mutation status in familial adenomato