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Aspartame degradation study using electrospray ionization mass spectrometry

โœ Scribed by Supason Pattanaargson; Chatchapol Sanchavanakit

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
96 KB
Volume
14
Category
Article
ISSN
0951-4198

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โœฆ Synopsis

Electrospray mass spectrometry was used to simultaneously determine aspartame (APM) and five of its degradation products; aspartic acid, aspartylphenylalanine, 5-benzyl-3,6-dioxo-2-piperazieacetic acid (diketopiperazine), phenylalanine, and phenylalanine methyl ester. Under the ionization conditions used, there was no interfering fragmentation for any of the six compounds, i.e., no fragmentation of the compound being tested into other species also being monitored. A study of APM degradation in solution at various pH's and at various temperatures using this method was performed.

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