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Asialoglycoprotein receptor targeted gene delivery using galactosylated polyethylenimine-graft-poly(ethylene glycol): In vitro and in vivo studies

โœ Scribed by Eun-Mi Kim; Hwan-Jeong Jeong; In-Kyu Park; Chong-Su Cho; Hyung-Bae Moon; Dae-Yeul Yu; Hee-Seung Bom; Myung-Hee Sohn; In-Joon Oh


Book ID
113691048
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
444 KB
Volume
108
Category
Article
ISSN
0168-3659

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Highly efficient gene transfer with degr
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## Abstract ## Background Polyethylenimine (PEI) is toxic although it is one of the most successful and widely used gene delivery polymers with the aid of the proton sponge effect. Therefore, development of new novel gene delivery carriers having high efficiency with less toxicity is necessary. #