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Ascorbic acid improves stability and pharmacokinetics of rifampicin in the presence of isoniazid

โœ Scribed by Rajaram, Subashini; Vemuri, Venkata Deepthi; Natham, Rajendran

Book ID
127258966
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
557 KB
Volume
100
Category
Article
ISSN
0731-7085

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โœ Helen M. Baldan; Helene J. De Rosa; Iguatemy L. Brunetti; Valdecir F. Ximenes; R ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 99 KB ๐Ÿ‘ 2 views

Tuberculosis chemotherapy involves combination of the drugs isoniazid (INH), rifampicin (RMP) and pyrazinamide (PYR) for a 6-month period. The present work investigated the influence of RMP and PYR on the pharmacokinetic parameters of INH when groups of rats were pre-treated for 21 days with INH alo