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Pharmacokinetic and safety evaluation of the use of ciprofloxacin on an isoniazid-rifampicin regimen in rabbits

✍ Scribed by Padilha, Elias Carvalho; Pires, Rodrigo Vieira; Filho, Marco Antonio Ferraz Nogueira; de Pontes Machado, Diego Vinicius; Baldan, Helen Mariana; Davanço, Marcelo Gomes; Campos, Michel Leandro; Brunetti, Iguatemy Lourenço; Peccinini, Rosângela Gonçalves

Book ID
118753205
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
163 KB
Volume
33
Category
Article
ISSN
0142-2782

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The effect of rifampicin and pyrazinamid
The effect of rifampicin and pyrazinamide on isoniazid pharmacokinetics in rats
✍ Helen M. Baldan; Helene J. De Rosa; Iguatemy L. Brunetti; Valdecir F. Ximenes; R 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 99 KB 👁 2 views

Tuberculosis chemotherapy involves combination of the drugs isoniazid (INH), rifampicin (RMP) and pyrazinamide (PYR) for a 6-month period. The present work investigated the influence of RMP and PYR on the pharmacokinetic parameters of INH when groups of rats were pre-treated for 21 days with INH alo