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Array Comparative Genomic Hybridization in Pediatric Acute Leukemias

✍ Scribed by Laskowska, Joanna; Szczepanek, Joanna; Styczyński, Jan; Tretyn, Andrzej

Book ID
120984083
Publisher
Informa plc
Year
2013
Tongue
English
Weight
168 KB
Volume
30
Category
Article
ISSN
0888-0018

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## Abstract Acute promyelocytic leukemia (APL) is typically associated with the t(15;17) that generates the __PML–RARA__ fusion protein. Animal models have shown that although the fusion protein is necessary, it is insufficient for the development of APL, implying that additional mechanisms are res