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Genome complexity in acute lymphoblastic leukemia is revealed by array-based comparative genomic hybridization

✍ Scribed by Strefford, J C; Worley, H; Barber, K; Wright, S; Stewart, A R M; Robinson, H M; Bettney, G; van Delft, F W; Atherton, M G; Davies, T


Book ID
110072191
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
362 KB
Volume
26
Category
Article
ISSN
0950-9232

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Genomewide array-based comparative genom
✍ Sivasundaram Karnan; Shinobu Tsuzuki; Hitoshi Kiyoi; Hiroyuki Tagawa; Ryozo Ueda πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 259 KB πŸ‘ 1 views

## Abstract Acute promyelocytic leukemia (APL) is typically associated with the t(15;17) that generates the __PML–RARA__ fusion protein. Animal models have shown that although the fusion protein is necessary, it is insufficient for the development of APL, implying that additional mechanisms are res