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Array comparative genomic hybridization analysis of adult acute leukemia patients

✍ Scribed by Duygu Yasar; Ihsan Karadogan; Guchan Alanoglu; Bahar Akkaya; Guven Luleci; Ozan Salim; Aysen Timuragaoglu; Gokce A. Toruner; Sibel Berker-Karauzum

Book ID
113513685
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
409 KB
Volume
197
Category
Article
ISSN
0165-4608

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## Abstract Acute promyelocytic leukemia (APL) is typically associated with the t(15;17) that generates the __PML–RARA__ fusion protein. Animal models have shown that although the fusion protein is necessary, it is insufficient for the development of APL, implying that additional mechanisms are res