Aromatic amine carcinogenesis: Activation and interaction with nucleic acid bases
β Scribed by Gilda Loew; B. S. Sudhindra; S. Burt; G. R. Pack; R. Macelroy
- Book ID
- 104579680
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 1022 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0020-7608
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π SIMILAR VOLUMES
Stacking of aromatic amino acids tryptophan (Trp), tyrosine (Tyr), phenylalanine (Phe), and histidine (His) with bases and base pairs of nucleic acids has been studied. Stacking energies of the amino acid-base (or base pair) complexes have been calculated by second-order perturbation theory. Our res
## Abstract A free radical was produced enzymatically by incubating benzo(a)pyrene with liver microsomes. This radical, identified as the 6βoxybenzo(a) pyrene radical, was sufficiently reactive to bind covalently with nucleic acid bases. Similar reactive free radicals were produced enzymatically fr
## Abstract A quinoxaline antibiotic triostin A has a bicyclic octadepsipeptide structure. Proton and carbonβ13 nmr spectra showed the presence of two symmetrical conformations favoring polar and nonpolar solvents, respectively. They interconvert slowly on the nmr time scale, and this slow intercon