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Ardipusilloside I induces apoptosis in human glioblastoma cells through a caspase-8-independent FasL/Fas-signaling pathway

✍ Scribed by Jian Xiong; Guang Cheng; HaiFeng Tang; Hai-Ning Zhen; Xiang Zhang

Book ID: 116454785
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 879 KB
Volume: 27
Category: Article
ISSN: 1382-6689
DOI: 10.1016/j.etap.2008.11.008

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## Abstract Exogenous β~2~‐microglobulin (β~2~m) induces significant apoptosis in the CCRF‐HSB‐2 human lymphoblastic leukemia cell line as detected by DNA fragmentation, DAPI staining and annexin V binding assay. β~2~m treatment induced the release of cytochrome c and apoptosis‐inducing factor (AIF