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ExoS of Pseudomonas aeruginosa induces apoptosis through a Fas receptor/caspase 8-independent pathway in HeLa cells

✍ Scribed by Mounia Alaoui-El-Azher; Jinghua Jia; Wei Lian; Shouguang Jin

Book ID: 109037288
Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 533 KB
Volume: 8
Category: Article
ISSN: 1462-5814
DOI: 10.1111/j.1462-5822.2005.00624.x

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## Abstract A20 was originally characterized as a TNF‐inducible gene in human umbilical vein endothelial cells. As an NF‐κB target gene, A20 is also induced in many other cell types by a wide range of stimuli. Expression of A20 has been shown to protect from TNF‐induced apoptosis and also functions