2-Deoxy-scyllo-inosose 1 and 2-deoxy-scyllo-inosamine 2 are two of the key intermediates on the biosynthetic pathway to 2-deoxystreptamine-containing aminoglycoside antibiotics. Convenient syntheses of 1, 2 and tritium-labelled 2 via stereoselective deoxygenation of myo-inositol using LTBH are repor
Approaches to the synthesis of CF2-analogues of 2-deoxy-2-aminoglycosides
β Scribed by Florent Poulain; Eric Leclerc; Jean-Charles Quirion
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- French
- Weight
- 341 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0040-4039
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The reaction of methyl 4,6-O-benzylidene-3-O-benzyl-2-O-trifluoromethanesulfonyl-beta-D- glucopyranoside in acetonitrile at 75 degrees C for 30 min with [18F]tetra-n-butylammonium fluoride, followed by silica gel column chromatographic purification, gave the corresponding [18F]methyl 4,6-O-benzylide
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Addition oP C,F'-dialkylphosphorodithioic acids to fully protected 1,2-unsaturated hsxo-and pentopyranoses gives S-(2-deoxy-glycosyl)-phosphorodithioates 'P -OH RO' 'SH -# H /OR HS-l'OR 2 2 Scheme I 2oa the &\_-adducte. The observed Oc'/s ratio was 89:ll and 92:8, respectively. pllso in these cases