Applications of solid supported azide anion: a one-pot, two-step preparation of functionalized 1,2,3-triazoles
β Scribed by Benjamin E Blass; Keith R Coburn; Amy L Faulkner; William L Seibel; Anil Srivastava
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 266 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Functionalized 1,2,3-triazoles were prepared in a one-pot, two-step synthesis from alkyl halides and alkynes using a polymer supported azide. Two different base resins were examined. The chemistry is suitable for the preparation of combinatorial libraries.
π SIMILAR VOLUMES
A one-pot, two-step protocol for the microwave-assisted solid-phase synthesis of substituted benzoxazoles has been developed starting from different polymer-bound esters we previously designed as solidsupported reagents (SSRs) for the acylation of amines, alcohols and phenols. The combination of a p
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## Abstract The reactive 1β:β1 zwitterionic intermediate formed by the addition of isocyanides to dialkyl acetylenedicarboxylates was trapped with 4βarylurazoles to produce the highly functionalized pyrazolo[1,2β__a__][1,2,4]triazoles **5** in good yields (__Table__). The structures of the products