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Monosubstituted 1,2,3-triazoles from two-step one-pot deprotection/click additions of trimethylsilylacetylene

✍ Scribed by James T. Fletcher; Sara E. Walz; Matthew E. Keeney

Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
263 KB
Volume
49
Category
Article
ISSN
0040-4039

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ChemInform Abstract: Monosubstituted 1,2
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## Abstract The reaction works best with organic bromides: 1,3‐dipolar cycloaddition of the resulting alkyl‐ and aryl azides with terminal alkynes affords disubstituted 1,2,3‐triazoles regioselectively.