𝔖 Bobbio Scriptorium
✦   LIBER   ✦

One-Pot Three-Component Synthesis of Highly Functionalized 2,3-Dihydro-1,3-dioxo-1H,5H-pyrazolo[1,2-a][1,2,4]triazoles

✍ Scribed by Mehdi Adib; Mohammad Hosein Sayahi; Niusha Mahmoodi; Hamid Reza Bijanzadeh

Publisher
John Wiley and Sons
Year
2006
Tongue
German
Weight
69 KB
Volume
89
Category
Article
ISSN
0018-019X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The reactive 1 : 1 zwitterionic intermediate formed by the addition of isocyanides to dialkyl acetylenedicarboxylates was trapped with 4‐arylurazoles to produce the highly functionalized pyrazolo[1,2‐a][1,2,4]triazoles 5 in good yields (Table). The structures of the products 5a–h were corroborated spectroscopically (IR, ^1^H‐ and ^13^C‐NMR), by EI‐MS, and elemental analysis. A possible mechanism for this reaction is proposed (Scheme).

📜 SIMILAR VOLUMES

ChemInform Abstract: One-Pot Three-Compo
ChemInform Abstract: One-Pot Three-Component Synthesis of 3-Amino-5,8-dioxo-5,8-dihydro-1H-pyrazolo[1,2-a]pyridazines (IV).
✍ Mehdi Adib; Somayeh Aali Koloogani; Alireza Abbasi; Hamid Reza Bijanzadeh 📂 Article 📅 2008 🏛 John Wiley and Sons ⚖ 25 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

One-Pot Synthesis of 4-(2,3-Dihydro-2-hy
One-Pot Synthesis of 4-(2,3-Dihydro-2-hydroxy-1,3-dioxo-1H-inden-2-yl)-Substituted 1-Aryl-1H-pyrazole-3-carboxylates via a Tandem Three-Component Reaction
✍ Abdolali Alizadeh; Ameneh Zarei; Atieh Rezvanian 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 German ⚖ 191 KB

## Abstract The hitherto unreported, highly functionalized 1__H__‐pyrazole‐3‐carboxylates **3** have been synthesized in good yields __via__ a one‐pot three‐component domino reaction of phenylhydrazines, dialkyl acetylenedicarboxylates, and ninhydrin under mild conditions for the first time. No co‐

An Efficient One-Pot, Four-Component Syn
An Efficient One-Pot, Four-Component Synthesis of {[(1H-1,2,3-Triazol-4-yl)methoxy]phenyl}-1H-pyrazolo[1,2-b]phthalazine-5,10-dione Derivatives
✍ Laleh Torkian; Minoo Dabiri; Peyman Salehi; Morteza Bararjanian 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 German ⚖ 234 KB

## Abstract The 1‐{[(1__H__‐1,2,3‐Triazol‐4‐yl)methoxy]phenyl}‐1__H__‐pyrazolo[1,2‐__b__]phthalazine‐5,10‐dione derivatives **5** were synthesized by a simple and efficient method, __i.e.__, by the four‐component, one‐pot condensation reaction of phthalohydrazide **4**, a (propargyloxy)benzaldehyde

A Facile One-Pot Synthesis of Functional
A Facile One-Pot Synthesis of Functionalized 1,5-Dihydro-2H-[1]benzopyrano[2,3-b]pyridin-5-ones
✍ Abbas Ali Esmaeili; Omid Ghareghani 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 German ⚖ 77 KB 👁 1 views

## Abstract The highly reactive 1 : 1 intermediate generated in the reaction between dialkyl acetylenedicarboxylate (=but‐2‐ynedioic acid dialkyl ester) **4** and triphenylphosphine was trapped by 2‐amino‐4‐oxo‐4__H__‐1‐benzopyran‐3‐carboxaldehydes **5** to yield highly functionalized dialkyl‐1,5‐d