𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A Facile One-Pot Synthesis of Functionalized 1,5-Dihydro-2H-[1]benzopyrano[2,3-b]pyridin-5-ones

✍ Scribed by Abbas Ali Esmaeili; Omid Ghareghani

Publisher
John Wiley and Sons
Year
2007
Tongue
German
Weight
77 KB
Volume
90
Category
Article
ISSN
0018-019X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The highly reactive 1 : 1 intermediate generated in the reaction between dialkyl acetylenedicarboxylate (=but‐2‐ynedioic acid dialkyl ester) 4 and triphenylphosphine was trapped by 2‐amino‐4‐oxo‐4__H__‐1‐benzopyran‐3‐carboxaldehydes 5 to yield highly functionalized dialkyl‐1,5‐dihydro‐5‐oxo‐1‐phenyl‐2__H__‐[1]benzopyrano[2,3‐b]pyridine‐2,3‐dicarboxylates in high yield.

📜 SIMILAR VOLUMES

A Facile Synthesis of [1]Benzopyrano[4,3
A Facile Synthesis of [1]Benzopyrano[4,3-b]pyridin-5-ones
✍ Ivano, Ivo C. ;Karagiosov, Stoyan K. ;Simeonov, Mario F. 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 455 KB

## Abstract The title compounds 5a‐c and 7a‐m have been prepared by Vilsmeier formylation of 4‐aminocoumarins 1 yielding aldehydes 2, and subsequent condensation of 2 with C‐H acids in the presence of piperidine. This condensation probably proceeds via the intermediate ylidenemalonic esters 4. By m