𝔖 Bobbio Scriptorium
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Applications and Simulations of a Discontinuous Oral Absorption Pharmacokinetic Model

✍ Scribed by Jennifer Wright Witcher; F. Douglas Boudinot

Book ID
110348492
Publisher
Springer US
Year
1996
Tongue
English
Weight
693 KB
Volume
13
Category
Article
ISSN
0724-8741

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πŸ“œ SIMILAR VOLUMES

DISCONTINUOUS ORAL ABSORPTION PHARMACOKI
DISCONTINUOUS ORAL ABSORPTION PHARMACOKINETIC MODEL AND BIOAVAILABILITY OF 1-(2-FLUORO-5-METHYL-Ξ²-L-ARABINOFURANOSYL)URACIL (L-FMAU) IN RATS
✍ Jennifer D. Wright; Tianwei Ma; Chung K. Chu; F. Douglas Boudinot πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 595 KB

## 1-(2-fluoro-5-methyl-&L-arabinofuranosyl)uracil (L-FMAU) , the L isomer of FMAU, has shown potent activity against hepatitis B virus and Epstein-Barr virus. L-FMAU showed double peaks in the plasma concentration versus time profiles following oral administration to rats, indicating discontinuous