𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Applications of Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation During Regulatory Review

✍ Scribed by Zhao, P; Zhang, L; Grillo, J A; Liu, Q; Bullock, J M; Moon, Y J; Song, P; Brar, S S; Madabushi, R; Wu, T C

Book ID
109846199
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
344 KB
Volume
89
Category
Article
ISSN
0009-9236

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Physiologically based pharmacokinetic (P
Physiologically based pharmacokinetic (PBPK) modeling of disposition of epiroprim in humans
✍ Olivier Luttringer; Frank-Peter Theil; Patrick Poulin; Anne H. Schmitt-Hoffmann; πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 256 KB

The objective of this study was to use in synergy physiologically based and empirical approaches to estimate the drug-specific input parameters of PBPK models of disposition to simulate the plasma concentration-time profile of epiroprim in human. The estimated input parameters were the tissue:plasma

Determination of the rat tissue partitio
Determination of the rat tissue partitioning of endotoxin in vitro for physiologically-based pharmacokinetic (PBPK) modeling
✍ Ivan A. Ross; Philip P. Sapienza; Darcy E. Hanes; Widmark Johnson; Chung S. Kim πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 96 KB

## Abstract The biosynthetically double‐labeled lipopolysaccharide (LPS), containing ^3^H‐labeled on the fatty acyl‐chains and ^14^C‐labeled on the glucosamine of __Salmonella enterica serotype typhimurium__, was isolated from bacteria grown in proteose peptone‐beef extract (PPBE) medium in the pre