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Application of a Gamma Model of Absorption to Oral Cyclosporin

✍ Scribed by Dr Jean Debord, Eléonore Risco, Michel Harel, Yannick Le Meur, Mathias Büchler, Gérard Lachâtre, Chantal Le Guellec, Pierre Marquet

Book ID
119926349
Publisher
Springer International Publishing AG
Year
2001
Tongue
English
Weight
167 KB
Volume
40
Category
Article
ISSN
0312-5963

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Apparent dose-dependent oral absorption
Apparent dose-dependent oral absorption of cyclosporin a in rats
✍ Clarence T. Ueda; Michel Lemaire; Guy Gsell; Pierrette Misslin; Kurt Nussbaumer 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 English ⚖ 520 KB

The oral absorption of cyclosporin A (CyA) was studied in rats after 6, 12, 18, and 23 mg kg-' doses were given in an olive oil solution to determine if CyA absorption from the gastrointestinal tract was dose-dependent. Using serial blood samples obtained at various times after the respective doses,