Denaturing gradient gel electrophoresis
β
Dubel, Jacqueline R. ;Finwick, Raymond ;Hejtmancik, J. Fielding
π
Article
π
1991
π
John Wiley and Sons
π
English
β 616 KB
A method for detection of the M and Z alleles of the alpha l-antitrypsin deficiency (AAT) gene has been developed using denaturing gradient gel electrophoresis (DGGE) of DNA samples amplified in vitro by the polymerase chain reaction. Amplification of the 90 nucleotides surrounding the Z mutation si