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Application of phase partitioning and thiophilic adsorption chromatography to the purification of monoclonal antibodies from cell culture fluid

✍ Scribed by Barbara Sulk; Gerd Birkenmeier; Gerhard Kopperschläger


Book ID
118902630
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
386 KB
Volume
149
Category
Article
ISSN
0022-1759

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The usefulness of thiophilic adsorption chromatography for the purification of rat IgG2b monoclonal antibodies has been evaluated. This approach has not shown specificity for immunoglobulins; therefore, to minimize potential interferences, the purification was carried out from supernatants of hybrid