Application of heteronuclear NOESY and COSY two-dimensional NMR experiments to sequencing peptides
β Scribed by Peter L Rinaldi; Frederick J Swiecinski
- Book ID
- 107798244
- Publisher
- Elsevier Science
- Year
- 1989
- Weight
- 270 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0022-2364
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π SIMILAR VOLUMES
The novel application of 2D heteronuclear NMR experiments to a single-stranded RNA fragment 5'-GCAU\*GGCU\*ACU\*U\*-3' labelled with 5-fluorouridine (U\*) at four sites is reported. Heteronuclear equivalents of COSY and NOESY experiments are described, both implemented in the phase-sensitive mode. T
## Abstract Several new protonβdetected heteronuclear twoβdimensional (2D) nmr techniques are presented that exhibit the features of __selection__ and __editing__ of multiplicity. The theoretical basis of the new features is briefly discussed and the application of the 2D techniques to a thioanalog