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Application of carboxypeptidase C for peptide synthesis

✍ Scribed by D. Steinke; M.R. Kula

Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
445 KB
Volume
12
Category
Article
ISSN
0141-0229

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Propargyl pentafluorophenyl carbonate was synthesised in quantitative yield by the reaction of propargyl chloroformate and pentafluorophenol. All the N-propargyloxycarbonyl (N-Poc) amino acids were obtained in good yield. The use of Poc-OPfp in peptide synthesis has been explored.