𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis and applications of propargyl pentafluorophenyl carbonate for peptide synthesis

✍ Scribed by Ramakrishna G Bhat; Erwan Kérourédan; Emmanuel Porhiel; Srinivasan Chandrasekaran

Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
52 KB
Volume
43
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

Propargyl pentafluorophenyl carbonate was synthesised in quantitative yield by the reaction of propargyl chloroformate and pentafluorophenol. All the N-propargyloxycarbonyl (N-Poc) amino acids were obtained in good yield. The use of Poc-OPfp in peptide synthesis has been explored.

📜 SIMILAR VOLUMES

Enzymatic synthesis of isotopically labe
Enzymatic synthesis of isotopically labelled serine and tryptophan for application in peptide synthesis
✍ J. Paul G. Malthouse; Teresa B. Fitzpatrick; John J. Milne; Leif Grehn; Ulf Ragn 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 102 KB 👁 2 views

L-[1.2-13C2, 15N]Serine was prepared from [1,2-13C2, 15N]glycine on a gram scale by the use of the enzyme serine hydroxymethyltransferase. The reaction was monitored by 13C-NMR spectroscopy. This is the first simultaneously 13C- and 15N-labelled serine isotopomer so far reported. Part of the product