The pattern of nuclease degradation observed for an antisense phosphorothioate oligonucleotide in pig kidney was determined using liquid chromatography/electrospray mass spectrometry (LC/ESI-MS) and LC/ESI-MS/MS with a quadrupole ion trap mass spectrometer. Metabolites were separated by length using
Application of a secondary ion mass spectrometer as a detector in liquid chromatography
β Scribed by A. Benninghoven; A. Eicke; M. Junack; W. Sichtermann; J. Krizek; H. Peters
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 365 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1076-5174
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