Efficient solid-phase synthesis of sulfa
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Kouki Kitagawa; Chikako Aida; Hidetoshi Fujiwara; Takeshi Yagami; Shiroh Futaki
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Article
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1997
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Elsevier Science
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French
⚖ 272 KB
An efficient Fmoc-based solid-phase method for the synthesis of sulfated tyrosine-containing peptides is described. This synthetic approach involves two key features: (1) use of the 2-chlorotrityl resin as a solid support, and (2) a two-step cleavage/deprotection protocol. Various molecular forms of