There is an increasing interest in identifying potent cancer preventive and therapeutic agents against prostate cancer (PCA). In a recent study, we showed that a polyphenolic fraction isolated from grape seeds (hereafter referred to as GSP) that is substantially rich in antioxidant procyanidins exer
Apoptosis induction in DU-145 human prostate carcinoma cells
β Scribed by Luciana Dini
- Book ID
- 116915133
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 470 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-8166
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## Abstract A longβterm tissue culture cell line has been derived from a human prostate adenocarcinoma metastatic to the brain. The cell line, DU 145, has been passaged 90 times __in vitro__ over a period of 2 years. The cells are epithelial, grow in isolated islands on plastic Petri dishes, and fo
## Abstract Development of effective agents for treatment of hormoneβrefractory prostate cancer has become a national medical priority. We have reported recently that apigenin (4β²,5,7βtrihydroxyflavone), found in many common fruits and vegetables, has shown remarkable effects in inhibiting cell gro