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Anisomycin activates JNK and sensitises DU 145 prostate carcinoma cells to Fas mediated apoptosis

✍ Scribed by Curtin, J F; Cotter, T G

Book ID: 109997400
Publisher: Nature Publishing Group
Year: 2002
Tongue: English
Weight: 132 KB
Volume: 87
Category: Article
ISSN: 0007-0920
DOI: 10.1038/sj.bjc.6600612

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## Abstract Androgen‐independent prostate cancers express high levels of Bcl‐2, and this over‐expression of Bcl‐2 protects prostate cancer cells from undergoing apoptosis. Ursolic acid (UA) has demonstrated an anti‐proliferative effect in various tumor types. The aim of this study is to evaluate th