Apolipoprotein E genotype and psychosis
โ Scribed by Ruriko Igata-Yi; Tomohide Igata; Kouko Ishizuka; Takemi Kimura; Shinichi Sakamoto; Shoichi Katsuragi; Junichi Takamatsu; Taihei Miyakawa
- Book ID
- 118511040
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 184 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0006-3223
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Patients with late paraphrenia or late onset schizophrenia frequently have associated cognitive impairment which may in some cases progress to a recognized dementia. The frequency of the apoE ~4 allele is high in individuals who develop Alzheimer's disease. Twenty-three patients with late paraphreni
We investigated the association between schizophrenia and the allelic polymorphism in the apolipoprotein E (Apo E) gene in 51 schizophrenic patients and 35 controls. The Apo E4 allele was equally represented in the schizophrenic group (16%) and the control group (20%) suggesting no association betwe