Apolipoprotein E genotype in schizophrenia

✍ Scribed by Joober, R. ;Rouleau, R. ;Fon, E. ;Lal, S. ;Palmour, R. ;Bloom, D. ;Labelle, A. ;Benkelfat, C.

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 124 KB
• Volume: 67
• Category: Article
• ISSN: 0148-7299
• DOI: 10.1002/ajmg.1320670204

✦ Synopsis

We investigated the association between schizophrenia and the allelic polymorphism in the apolipoprotein E (Apo E) gene in 51 schizophrenic patients and 35 controls. The Apo E4 allele was equally represented in the schizophrenic group (16%) and the control group (20%) suggesting no association between schizophrenia and the Apo E4 allele.

The apolipoprotein E (Apo E) is a polymorphic (E2, E3, and E4) lipoprotein involved in the transmembrane