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ApoE2 Allele, Down's Syndrome, and Dementia

✍ Scribed by M. C. ROYSTON; D. MANN; S. PICKERING-BROWN; F. OWEN; R. PERRY; R. RAGBHAVAN; C. KHIN-NU; S. TYNER; K. DAY; R. CROOK; J. HARDY; G. W. ROBERTS

Book ID
119873370
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
260 KB
Volume
777
Category
Article
ISSN
0890-6564

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The relationship between apo E genotypes and risk of dementia in Down syndrome is not clear. Accordingly, we have analysed this locus in 20 demented and 25 nondemented individuals with Down syndrome and combined these data with other studies in a meta-analysis. The meta-analysis revealed an estimate