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Antitumor agents LIX: Effects of quassinoids on protein synthesis of a number of murine tumors and normal cells

✍ Scribed by I. H. Hall; Y. F. Liou; K. H. Lee; S. G. Chaney; W. Willingham Jr.


Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
589 KB
Volume
72
Category
Article
ISSN
0022-3549

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Antitumor agents LII: The effects of mol
✍ Iris H. Hall; Y. F. Liou; K. H. Lee πŸ“‚ Article πŸ“… 1982 πŸ› John Wiley and Sons 🌐 English βš– 551 KB

o Molephantinin, a germacranolide, has previously been shown to possess antineoplastic activity in rodents. The principle effect of molephantinin on Ehrlich ascites carcinoma cells was to depress DNA and protein synthesis both in uiuo and in uitro. DNA synthesis was inhibited a t the following sites