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Antitumor Agents. 181. † Synthesis and Biological Evaluation of 6,7,2‘,3‘,4‘-Substituted-1,2,3,4-tetrahydro-2-phenyl-4-quinolones as a New Class of Antimitotic Antitumor Agents

✍ Scribed by Xia, Yi; Yang, Zheng-Yu; Xia, Peng; Bastow, Kenneth F.; Tachibana, Yoko; Kuo, Sheng-Chu; Hamel, Ernest; Hackl, Torben; Lee, Kuo-Hsiung


Book ID
120022644
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
253 KB
Volume
41
Category
Article
ISSN
0022-2623

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Antitumor Agents. Part 181. Synthesis and Biological Evaluation of 6,7,2',3',4'-Substituted-1,2,3,4-tetrahydro-2-phenyl-4-quinolones as a New Class of Antimitotic Antitumor Agents. -Some of the most active compounds are (IVd) and (VI) showing strong cytotoxic effects with very low ED 50 . Three act