Heparin stimulates 2-3-fold, in a concentration-dependent manner, the synthesis of heparan sulfate secreted by cultured endothelial cells. The increase in synthetic rate takes place immediately after exposure of the cells to heparin, affects only heparan sulfate, and i s specific for the endothelial
Antithrombotic agents stimulate the synthesis and modify the sulfation pattern of a heparan sulfate proteoglycan from endothelial cells
β Scribed by Maria A.S. Pinhal; Jeanine M. Walenga; Walter Jeske; Debra Hoppensteadt; Carl P. Dietrich; Jawed Fareed; Helena B. Nader
- Book ID
- 118371514
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 809 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0049-3848
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