Antisera against 13,14-dihydro-15-keto-prostaglandin E2
โ Scribed by B.A. Peskar; A. Holland; B.M. Peskar
- Book ID
- 115905026
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- English
- Weight
- 189 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0014-5793
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The main metabolite of prostaglandin E, (PGE2) 13,14-dihydro-Sketo-PGE, readily dehydrates and can subsequently form a cyclic derivative. This problem can be overcome by the immediate formation of oximes of the 9 and 15 ketones in aqueous solution followed by subsequent extraction, methylation and t
## Abstract Chemical and enzymatic tools were employed to synthesize [1,1โ^18^O~2~]โprostaglandin (PG) E1, [1,1โ^18^O~2~]โ13,14โdihydroโ15โketoโPGE~1~ and [5,6โ^3^H~2~]โ13,14โdihydroโ15โketoโPGE~1~ starting from the corresponding unlabelled compounds adn [5,6โ^3^H~2~]โPGE~1~, respectively. Reaction