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Antipyretic effect of central [Pyr1]apelin13 on LPS-induced fever in the rat

✍ Scribed by Hatzelmann, Thomas; Harden, Lois M.; Roth, Joachim; Gerstberger, Rüdiger

Book ID
122998716
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
598 KB
Volume
184
Category
Article
ISSN
0167-0115

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✍ R. B. Ashorobi 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 98 KB 👁 2 views

Fever was induced in rats with a single i.p. injection of 30 g/kg E. coli endotoxin. The effect of the alcohol leaf extract of Azadirachta indica was investigated in this model. Pretreatment of rats with the leaf extract (125-375 mg/kg) did not significantly reduce endotoxin-induced fever. The recta