Antipsoriatic activity of flavonoids isolated from the roots of Sophora flavescens Aiton
- Book ID
- 116588926
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 43 KB
- Volume
- 66
- Category
- Article
- ISSN
- 1097-6787
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## Abstract Three new flavonoids, which are isoprenylated by fused 2,2βdimethylβ3,4βdihydroβ2__H__βpyran moieties, were isolated from the roots of __Sophora flavescens__ and named flavenochromanes AβC (**1**β**3**). Their structures were elucidated by spectroscopic methods, including 2DβNMR techniq
The cytotoxicity-guided fractionation of the roots of Sophora flavescens (Leguminosae) extracts led to the isolation of 15 active principles 1-15, responsible for cytotoxicity against five kinds of cultured human tumour cell lines, i.e. A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (skin), X