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Antioxidant compounds have potent anti-fibrillogenic and fibril-destabilizing effects for α-synuclein fibrils in vitro

✍ Scribed by Kenjiro Ono; Masahito Yamada

Book ID
111179424
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
398 KB
Volume
97
Category
Article
ISSN
0022-3042

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## Abstract The aggregation of alpha‐synuclein (αS) in the brain has been implicated as a critical step in the development of Lewy body diseases (LBD) and multiple system atrophy (MSA). Among the antioxidant strategies proposed, increasing evidence points to the possibility of achieving neuroprotec