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Anti-aggregation and fibril-destabilizing effects of sex hormones on α-synuclein fibrils in vitro

✍ Scribed by Mie Hirohata; Kenjiro Ono; Akiyoshi Morinaga; Tokuhei Ikeda; Masahito Yamada

Book ID
116459498
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
454 KB
Volume
217
Category
Article
ISSN
0014-4886

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## Abstract The aggregation of alpha‐synuclein (αS) in the brain has been implicated as a critical step in the development of Lewy body diseases (LBD) and multiple system atrophy (MSA). Among the antioxidant strategies proposed, increasing evidence points to the possibility of achieving neuroprotec