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Antimalarial activity and synthesis of new trisubstituted pyrimidines

✍ Scribed by Anu Agarwal; Kumkum Srivastava; S.K. Puri; Prem M.S. Chauhan

Book ID
108073646
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
135 KB
Volume
15
Category
Article
ISSN
0960-894X

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## Abstract A simple and straightforward methodology towards the synthesis of 2,4,5‐trisubstituted pyrimidines has been developed by one‐step reaction of isoflavones with thiourea or guanidine. Ten 2‐mercapto‐4,5‐diphenylpyrimidines and eight 2‐amino‐4,5‐diphenylpyrimidines were reported. All of th