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Antimalarial Activity of 2,4,6-Trisubstituted Pyrimidines.

โœ Scribed by Anu Agarwal; Kumkum Srivastava; S. K. Puri; Prem M. S. Chauhan


Publisher
John Wiley and Sons
Year
2005
Weight
14 KB
Volume
36
Category
Article
ISSN
0931-7597

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## Abstract A simple and straightforward methodology towards the synthesis of 2,4,5โ€trisubstituted pyrimidines has been developed by oneโ€step reaction of isoflavones with thiourea or guanidine. Ten 2โ€mercaptoโ€4,5โ€diphenylpyrimidines and eight 2โ€aminoโ€4,5โ€diphenylpyrimidines were reported. All of th