The crude dry latex of Calotropis procera possesses a potent antiinflammatory activity. The antiinflammatory activity of petroleum ether, acetone, methanol and aqueous extracts of dry latex of Calotropis procera was tested in the carrageenan induced rat paw oedema model. All the fractions exhibited
Antiinflammatory activity of extracts of Biophytum sensitivum in carrageenin-induced rat paw oedema
โ Scribed by S. M. Jachak; F. Bucar; Th. Kartnig
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 35 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0951-418X
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โฆ Synopsis
The antiinflammatory activity of aqueous and methanol extracts of aerial parts, an aqueous extract of roots as well as ultrafiltration fractions of a methanol extract of roots of Biophytum sensitivum were evaluated in the carrageenin induced rat paw oedema model. All the extracts except the methanol extract of aerial parts exhibited antiinflammatory activity, but inhibition of oedema was found to be maximum with aqueous extracts.
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An extract of Cestrum parqui aerial parts in methanol:water (1:1) showed inhibition of carrageenin-induced oedema. The aggregation of human blood platelets induced by adenosine diphosphate and platelet activating factor was also inhibited (IC 50 s were 3 and 2 mg/mL, respectively). On the contrary,
Tripterygium wilfordii Hook F (TWH), commonly known as the Thunder-God-Vine, is a popular remedy for rheumatism in southern China. In this study, we investigated the effect of T2 (an extract from TWH) on adjuvant-induced paw oedema in rats and inflammatory mediators. The results showed that an intra