## Abstract Viruses produced by two Moloney lymphoma sublines (Y and Yr), and their hybrids with a mouse L cell subline (YL and YrL) were tested for antigenic conversion and focus induction on JLS‐V9 and D56 (S + L −) cells. Two infectivity patterns were encountered. Both indicator cell lines were
Antigenic relatedness of simian C-type viruses
✍ Scribed by S. R. S. Rangan
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- French
- Weight
- 564 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0020-7136
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✦ Synopsis
Abstract
The two simian C‐type viruses, gibbon lymphoma (GLV) and simian sarcoma (SSV‐1), are compared for their antigenic relatedness by serum‐neutralization techniques appropriate for the respective virus. While GLV was neutralized completely by its homologous antiserum, its replication was merely delayed by anti‐SSV‐1 serum. Both anti‐SSV‐1 and anti‐GLV antisera neutralized SSV‐1 and its associated virus (SSAV‐1). It is concluded that the simian viruses are antigenically related but distinct from each other and unrelated to feline leukemia virus. The results also suggest that SSV‐1 and SSAV‐1 possess identical envelope antigens.
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