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Antifilarial agents. 3-Aminopyrrolidine and 1,4-diazabicyclo[3.2.1]octane derivatives as analogs of diethylcarbamazine

โœ Scribed by Sturm, Priscilla A.; Cory, Michael; Henry, David W.; McCall, J. W.; Ziegler, J. B.


Book ID
126773480
Publisher
American Chemical Society
Year
1977
Tongue
English
Weight
704 KB
Volume
20
Category
Article
ISSN
0022-2623

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Synthesis and biological evaluation of 2
โœ Sheung-Tsam Kam; Robert N. Hanson; Philip S. Portoghese ๐Ÿ“‚ Article ๐Ÿ“… 1980 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 505 KB

Three prostaglandin endoperoxide analogs that possess the 2,3-diazabicyclo[2.2.1]heptane skeleton were synthesized and evaluated for activity in human platelets and in the rat fundus. All three compounds were inactive in inhibiting or stimulating platelet aggregation. One compound possessed weak con