Anticonvulsant effect of felbamate in th
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O. Giorgi; G. Carboni; V. Frau; M. Orlandi; V. Valentini; A. Feldman; M. G. Cord
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Article
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1996
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Springer-Verlag
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English
⚖ 661 KB
The present study was designed to examine the ability of felbamate, a novel antiepileptic agent, to antagonize the increase in seizure severity (i.e., chemical kindling) produced by chronic treatment with initially subconvulsant doses of pentylenetetrazol (PTZ). Rats were treated with PTZ (30 mg/kg,