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Antiepileptic Effects of Tiagabine, a Selective GABA Uptake Inhibitor, in the Rat Kindling Model of Temporal Lobe Epilepsy

✍ Scribed by Kiyoshi Morimoto; Hitoshi Sato; Yoshitaka Yamamoto; Takemi Watanabe; Hiroshi Suwaki

Book ID
109106423
Publisher
Wiley (Blackwell Publishing)
Year
1997
Tongue
English
Weight
882 KB
Volume
38
Category
Article
ISSN
0013-9580

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Temporal lobe epilepsy (TLE) is one of the most commonly occurring and most intractable forms of seizure disorders in humans. The fundamental mechanisms underlying the pathogenesis of the disorder have, however, not yet been elucidated. El is an inbred mouse strain with genetic predisposition to epi